Time, cost and achieving good drug exposure with minimal API use at early lead identification stage are important priorities for getting your compound to the clinic. Solution Engine platform screens and identifies optimal physicochemical, formulation and ADME properties for your active and accelerates drug discovery and development process with the least cost.

Working with a partner who can effectively employ a multidisciplinary approach can improve efficiency and candidate success. Through BioDuro-Sundia's unique incorporation of formulation development and DMPK services, the BioDuro-Sundia Solution Engine can overcome issues of poor solubility and/or poor permeability (BCS II, III and IV), scarce APl supplies and the need for rapid selection of the best formulation approaches from Amorphous Solid Dispersions (ASD: Spray drying, Hot Melt Extrusion, precise precipitation or mesoporous silica), Lipid based formulations: solutions/suspensions/nano-emulsions/SEDDS/S MEDDS, nano-suspension and micronization. By integrating discovery and development, we develop a thorough understanding of your compounds and select optimal candidate for further development.

In-Vitro/In-Vivo Performance Screening for Screening ASD Formulations and Commercial Manufacturing